NGAL ELISA Kit (human)

CAT.NO. KIT 036 DELIVERY: 1-5 DAYS

Cat. No.

KIT 036

Product name

NGAL ELISA Kit (human)

Description

An ELISA for the in vitro determination of human NGAL in urine and plasma.

Assay range

10-1000 pg/mL

Assay time

4 hours

Limit of detection

4 pg/mL

Sample dilution

1/500 (Urine from healthy subjects)

Species reactivity (positive)

None

Storage

4°C

Target

Human NGAL (Neutrophil Gelatinase-Associated Lipocalin)

Background

NGAL is a new early biomarker for diagnosing acute kidney injury (AKI)

Under normal conditions, NGAL levels are low in urine and plasma, but they rise sharply from basal levels in response to kidney injury to reach diagnostic levels within a very short time - as much as 24 hours or more before any significant rise in serum creatinine.

Regulatory status

Not available in the USA for in vitro diagnostic use. For in vitro diagnostic use in the European Union, Canada and Iran. For research use only in all other territories.

Patent status

This product is protected by one or more U.S., European and/or foreign patents as listed on www.bioporto/about us/patents

Other information

Simple ELISA format - easy to perform Ready-to-use calibrators and working solutions Pre-coated ELISA strips All incubations performed at room temperature Easy storage All components are stored at 4°C Automation possible on open ELISA workstations

Hasse-Fielitz A, Haase M, Devarajan P (2014) Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evalsuation of current status. Ann Clin Biochem 51:335-351

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Cho E, Yang HN, Jo SK, Cho WY, Kim HK (2013) The role of urinary liver-type fatty acid-binding protein in critically ill patients. J Korean Med Sci. 28:100-105

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Di NM, Ficarella A, Ricci Z, Luciano R, Stoppa F, Picardo S, Picca S, Muraca M, Cogo P (2013)Impact of severe sepsis on serum and urinary biomarkers of acute kidney injury in critically ill children: an observational study. Blood Purif 35: 172-176

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Kashani K et al (2013) Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care 17:R25  

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Kift RL et al (2013) A comparison of the analytical performance of five commercially available assays for neutrophil gelatinase-associated lipocalin using urine. Ann Clin Biochem. 50: 236-244