DiscoverX PI3-Kinase (p110alpha(E542K) p85alpha) murine 14-791M 14-791M|产品详情|进口橙子视频旧款采购网

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DiscoverX PI3-Kinase (p110alpha(E542K) p85alpha) murine 14-791M

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DiscoverX PI3-Kinase (p110alpha(E542K) p85alpha) murine 14-791M

品牌：Eurofins DiscoverX

货号：14-791M

规格：14-791M

货期：DiscoverX

应用：

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品牌：DiscoverX 品名：PI3-Kinase (p110α(E542K)/p85α) murine 货号：14-791M 规格：250 µg

商品详情参考文献相关资料

品牌：DiscoverX
品名：PI3-Kinase (p110α(E542K)/p85α) murine
货号：14-791M
规格：250 µg

简要说明：

PI3-Kinase (p110α(E542K)/p85α) murine

Complex of N-terminal 6His-tagged recombinant, murine p110α full length, containing the mutation E542K, and untagged, recombinant, murine p85α full length. The E542K substitution is a somatic mutation in p110α that has been associated with tumours of the colon and brain. Combined in vitro and in vitro studies have shown that this mutation confers higher lipid kinase activity than wild type, and is able to induce oncogenic transformation. (Kang S. et al., PNAS, (2005);102: 802-807 and Zhao J.J. et al., PNAS, (2005);102:18443-18448).

产品介绍：

Target

PI3Kα/p85α

Expression System

Expressed by baculovirus in Sf21 insect cells

Application

Kinase Assay

Molecular Weight

129 kDa (p110α E542K), 84 kDa (p85α)

Accession Number

BC089038

Species

Mouse

Tag

6His

Purification Method

Ni2+/NTA-agarose

Content

Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution.

Storage

6 months at -70°C

Bulk Sizes

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