Catalogue number
ANT-081
Synonyms
Keratin, type I cytoskeletal 23, Cytokeratin-23, CK-23, Keratin-23, K23, KRT23, CK23, HAIK1.
Type
Mouse Anti Human Monoclonal.
Introduction
Cytokeratin 23 (KRT23) is a 422 amino acid intermediate filament protein. The human KRT23 gene is found on chromosome 17q21.2. Type I cytokeratins consist of acidic proteins which are organized in pairs of heterotypic keratin chains. The cytokeratin proteins have an essential role in differentiation, plus tissue specialization and function, and epithelial cells structure maintenance. Cytokeratins are portrayed to be differentiation markers in a number of epithelial cancers.
Clone
PAT2F6AT.
Immunogen
Anti-human KRT23 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KRT23 amino acids 271-422 purified from E. coli.
Ig Subclass
Mouse IgG1 heavy chain and k light chain.
Purification Method
KRT23 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Formulation
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.
Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Applications
KRT23 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:3000.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
