Catalogue number
ANT-530
Type
Mouse Anti Human Monoclonal.
Introduction
Immunoglobulin M (IgM) is a basic antibody produced by B cells. IgM is the first antibody to emerge in response to initial exposure to an antigen. IgM antibodies are found in the blood and lymph fluid and are the third most widespread serum Ig. Immunoglobulin M (IgM), being the 3rd most widespread serum Ig and exists in two forms- mostly as a pentamer (970kDa) but also as a hexamer. The pentameric IgM has 10 s since each monomer has two antigen s. Due to distance constraints in the hexameric complex, the J chain is found in pentameric IgM but not in the hexameric form. IgM antibodies, which appear early in the course of an infection, typically reappear to a smaller extent after additional exposure. IgM, as opposed to IgG antibodies, do not pass across the human placenta. These properties of IgM make it suitable for the diagnosis of infectious diseases.
Description
Monoclonal anti-human IgM is the antibody specific for the lateral flow immunoassay development, for dengue IgG/IgM test.
Purification Method
IgM antibody was purified from mouse ascitic fluids by Protein-A chromatography.
Purity
Greater than 90%.
Physical Appearance
Sterile Filtered clear colorless solution.
Formulation
IgM antibody solution contains Phosphate buffered saline pH 7.2.
Storage Procedures
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.
Applications
Lateral flow immunoassay.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
