Catalogue number
PRO-2364
Synonyms
Tumor-Associated Calcium Signal Transducer 2,Membrane
Component Chromosome 1 Surface Marker 1, Pancreatic Carcinoma Marker Protein
GA733-1,Cell Surface Glycoprotein Trop-2, GA733-1,TROP2, M1S1,
40kD Glycoprotein, Identified By Monoclonal Antibody GA733,Membrane
Component, Chromosome 1, Surface Marker 1, Gastrointestinal Tumor-Associated
Antigen GA7331,Pancreatic Carcinoma Marker Protein GA7331,Cell
Surface Glycoprotein TROP2,Epithelial Glycoprotein-1Truncated
TACSTD2,GA7331,EGP-1,EGP1,GP50, TACSTD2.
Introduction
Tumor-associated calcium signal transducer 2 (TACSTD2), is a member of to the EPCAM family. TACSTD2 is an intronless gene which encodes a carcinoma-associated antigen. TACSTD2 may act as a growth factor receptor and as a cell surface receptor that transduces calcium signals. Mutations of TACSTD2 have been associated with gelatinous drop-like corneal dystrophy.
Description
TACSTD2 Human Recombinant produced in Sf9 Baculovirus cells is a single, non-glycosylated polypeptide chain containing 253 amino acids (31-274a.a) and having a molecular mass of 28.6kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).
TACSTD2 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
TACSTD2 protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
ADPQDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ
NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLTHHH HHH.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
