Catalogue number
PRO-2163
Synonyms
THO Complex 7, Functional Spliceosome-Associated Protein
24, NIF3L1BP1, Ngg1-Interacting Factor 3-Like Protein 1-Binding Protein 1, Ngg1
Interacting Factor 3 Like 1 Binding Protein 1, NIF3L1-Binding Protein 1,
HTREX30, FSAP24, THO Complex 7 Homolog (Drosophila), THO Complex Subunit 7
Homolog, THO Complex 7 Homolog, fSAP24, hTREX30.
Introduction
THO Complex 7, also known as THOC7, is a component of the THO subcomplex of the TREX complex which couples mRNA transcription, processing and nuclear export, and which related to spliced mRNA. THOC7 is a protein coding gene which is essential for export of polyadenylated RNA. Furthermore, THOC7 is associated with RNA transport.
Description
THOC7 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and
having a molecular mass of 26.1kDa.THOC7 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
THOC7 protein solution (0. 5mg/ml) containing Phosphate
buffered saline (pH7.4) and 50% glycerol, 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMGAVTDD EVIRKRLLID GDGAGDDRRI NLLVKSFIKW CNSGSQEEGY
SQYQRMLSTL SQCEFSMGKT LLVYDMNLRE MENYEKIYKE IECSIAGAHE KIAECKKQIL QAKRIRKNRQ
EYDALAKVIQ HHPDRHETLK ELEALGKELE HLSHIKESVE DKLELRRKQF HVLLSTIHEL QQTLENDEKL
SEVEEAQEAS METDPKP.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
