Catalogue number
PRO-1746
Synonyms
Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase, CCDC44, Coiled-Coil Domain-Containing Protein 44, Coiled-Coil Domain Containing 44, Clone HQ0477 PRO0477p, Translational Activator Of Cytochrome C Oxidase 1, Translational Activator Of Mitochondrially-Encoded Cytochrome C Oxidase I.
Introduction
Translational
activator of mitochondrially encoded cytochrome c oxidase I (TACO1) belongs to
the TACO1 family. TACO1 is a mitochondrial protein which functions as a
translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations
in this gene are associated with Leigh syndrome.
Description
TACO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (61-297 a.a) and having a molecular mass of 28.8kDa.
TACO1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TACO1 protein solution (0.5mg/ml) containing 20mM
Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSNKWSKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAED
VKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
