Catalogue number
ENZ-839
Synonyms
HD Domain Containing 2, Hepatitis C Virus NS5A-Transactivated Protein 2, HCV NS5A-Transactivated Protein 2, C6orf74, NS5ATP2, Chromosome 6 Open Reading Frame 74, HD Domain-Containing Protein 2,DJ167O5.2, CGI-130, HDDC2.
Introduction
HD Domain Containing 2, also known as HDDC2 is a member of the HDDC2
family. HDDC2 is an enzyme which contains one HD domain and it is expected to
exhibit phosphohydrolase activity. It has been proposed that HDDC2 takes part in
nucleic acid metabolism, signal transduction and possibly other functions in
bacteria, archaea and eukaryotes. The HD domain consists of highly conserved
residues, in particular histidines or aspartates. Porphyria cutanea tarda,
Parkinson’s disease and Stickler syndrome have all been related with HDDC2.
Description
HDDC2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-204 a.a) and having a molecular mass of 25.8 kDa.
HDDC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
HDDC2 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMASVSSA TFSGHGARSL LQFLRLVGQL KRVPRTGWVY RNVQRPESVS DHMYRMAVMA MVIKDDRLNK DRCVRLALVH DMAECIVGDI APADNIPKEE KHRREEEAMK QITQLLPEDL RKELYELWEE YETQSSAEAK FVKQLDQCEM ILQASEYEDL EHKPGRLQDF YDSTAGKFNH PEIVQLVSEL EAERSTNIAA AASEPHS
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
