Catalogue number
ANT-123
Synonyms
Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma.
Type
Mouse Anti Human Monoclonal.
Introduction
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.
IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Clone
NYRhIFNg.
Immunogen
r.Human IFN-g.
Ig Subclass
Mouse IgG2a.
Purification Method
Ion exchange.
Formulation
1mg/ml in PBS (after reconstitution).
Shipping Conditions
Antibody is shipped lyophilized at ambient temperature.
Storage Procedures
In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
Solubility
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Titer
This antibody loses its antigen binding capacity when immobilized on plastic. Biological activity is determined by virus neutralization assay and MHC class II induction.
References
1.Title: Activation of human NK cells by plasmacytoid dendritic
cells and its modulation by CD4+T helper cells and CD4+CD25hiT regulatory cells
Publications: Eur. J. Immunol. 2005. 35:
2452–2458
Link: http://onlinelibrary.wiley.com/doi/10.1002/eji.200526069/epdf
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
