Catalogue number
CYT-887
Synonyms
Growth
Differentiation Factor 11, BMP11, Bone Morphogenetic Protein 11, BMP-11, GDF-11,
Growth/Differentiation Factor 11, Growth/differentiation factor 11.
Introduction
GDF-11 belongs to the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF-11 is a central developmental factor which controls muscular and neural development. In *****s, GDF-11 encourages cardiac hypertrophy reverse by the revival of cardiomyocytes.
Description
GDF11 Human Recombinant produced in E.Coli is a single, non-glycosylated
polypeptide chain containing 132 amino acids (299-407a.a) and having a
molecular mass of 14.8kDa.
GDF11 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
GDF11 protein solution (1mg/ml) containing 20mM Tris-HCl
(pH8.0) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH
SSGLVPRGSH MGSNLGLDCD
EHSSESRCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGQC EYMFMQKYPH THLVQQANPR GSAGPCCTPT
KMSPINMLYF NDKQQIIYGK IPGMVVDRCG CS.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
