Catalogue number
PRO-1734
Synonyms
Acyl-CoA Binding Domain Containing 6, Acyl-Coenzyme A
Binding Domain Containing 6, Acyl-CoA-Binding Domain-Containing Protein 6, ACBD6.
Introduction
Acyl-CoA
binding domain containing 6, also known as ACBD6 contains 1 ACB
(acyl-CoA-binding) domain and 2 ANK repeats. ACBD6 binds long-chain
acyl-coenzyme A molecules with a strong preference for unsaturated C18:1 CoA,
lower affinity for unsaturated C20:4-CoA, and extremely weak affinity for
saturated C16:0-CoA. Moreover ACBD6 does
not bind fatty acids. ACBD6 has been detected in placenta, umbilical cord
blood, CD34-positive hematopoietic progenitor cells and bone marrow.
Endotheliitis has been associated with ACBD6.
Description
ACBD6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 305 amino acids (1-282aa) and having a molecular mass of 33.5kDa.
ACBD6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
ACBD6 protein solution (0.5mg/ml) containing 20mM
Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMASSFLP AGAITGDSGG ELSSGDDSGE VEFPHSPEIE ETSCLAELFE KAAAHLQGLI QVASREQLLY LYARYKQVKV GNCNTPKPSF FDFEGKQKWE AWKALGDSSP SQAMQEYIAV VKKLDPGWNP QIPEKKGKEA NTGFGGPVIS SLYHEETIRE EDKNIFDYCR ENNIDHITKA IKSKNVDVNV KDEEGRALLH WACDRGHKEL VTVLLQHRAD INCQDNEGQT ALHYASACEF LDIVELLLQS GADPTLRDQD GCLPEEVTGC KTVSLVLQRH TTGKA.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
