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CF-Blue™ - anti mouse CD154 - Clone MR1 |产品详情|进口橙子视频旧款采购网




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    CF-Blue™ - anti mouse CD154 - Clone MR1
    品牌：Immunostep
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    CF-Blue™ - anti mouse CD154 - Clone MR1
    商品详情 参考文献 相关资料

    CF-Blue - anti Mouse CD154 - MR1

    Reference Size Price Quantity Add to cart
    90,00 € tax excl.

    200,00 € tax excl.

    Product Description

    • MR1
    • Armenian Hamster IgG
    • Flow Cytometry
    • CF-Blue
    • 0.5 mg/ml
    • Activated mouse Th1 clone D1.6
    • Mouse
    • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
    • RUO
    • CD154, clone MR1, is a mAb intended for RUO in the identification/enumeration of lymph that express CD154. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
    • Liquid
    • Store in the dark at 2-8 °C
    Mouse CFB Vial View larger
    CD154 (CD40 Ligand, gp39) is an accessory molecule expressed on activated T helper (CD4+) lymph ocytes. CD154 has also been detected on other types of leukocytes, including CD8+ T cells, medullary thymocytes, activated CD4+ NK-T cells, and human NK cells. CD154 plays an important role in costimulatory interactions between T and B lymph ocytes and between antigen-presenting cells and lymph ocytes, regulating the immune response at multiple levels. MR1 mAb inhibits in vitro activation of B lymph ocytes by T helper cells by blocking interaction of gp39 with CD40. In vitro interactions of T cells and antigen-presenting cells can also be blocked by the MR1 antibody. In vivo treatment with MR1 antibody blocks the development of experimental autoimmune disease, inhibits formation of germinal centers and generation of memory B cells, reduces T-lymph ocyte responses to allogeneic cells and allografts, prevents intrathymic deletion of self-reactive T lymph ocytes, and disrupts antigen-specific T-cell responses.
    • CD40 Ligand, gp39
    • 21947
    • 39 kD
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