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THY1 Antibody abx117215|产品详情|进口橙子视频旧款采购网




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    THY1 Antibody
    品牌:Abbexa
    货号:abx117215
    规格:100 μg
    货期:

    THY1 Antibody

    商品详情 参考文献 相关资料
    THY1 Antibody is a Rabbit Polyclonal antibody against THY1. THY1 is a GPI-anchored, developmentally regulated protein involved in various signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosisIt is highly expressed on the surface of ***** neurons and is thought to play a role in modulating adhesive and migRatory events, such as neurite extensionDecreased THY1 expression is associated with the development of epithelial ovarian cancer, revealing its role as a putative tumor suppressor gene of human ovarian cancerTHY1 knockout mice have impaired cutaneous immune responses and abnormal retinal developmentTHY1 is epigenetically regulated, or deregulated in some disease states, such as pulmonary fibrosisThe potentially reversible hypermethylation of the THY1 promoter offers the possibility of novel therapeutic options in this disease.

    Target THY1
    Reactivity Human, Mouse, Rat
    Host Rabbit
    Clonality Polyclonal
    Tested Applications WB, IHC
    Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
    Purification Affinity purified.
    Isotype IgG
    Conjugation Unconjugated
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Swiss Prot P04216
    Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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