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TRPV6 Antibody is a Rabbit Polyclonal antibody against TRPV6. The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV6 belongs to the V type subfamily, and it facilitates calcium entry across the plasma membrane in pancreas, placenta, and to a lesser extent stomach and kidney tissue. Furthermore, prostate cancer cells overexpress TRPV6, while benign prostate tissues do not express the protein, implying a role for TRPV6 in malignant growth.

Target	TRPV6
Reactivity	Human
Origin	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant fusion protein of human TRPV6.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 68 kDa/87 kDa Observed MW: 70 kDa
Swiss Prot	Q9H1D0
GeneID	55503
Gene Symbol	TRPV6
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.