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Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). This antibody is supplied as crude ascites.

Target	TNINI3
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human TNINI3.
Purification	Mouse Monoclonal Antibody (Mab) supplied as crude ascites.
Isotype	IgM
Conjugation	Unconjugated
Specificity	This TNINI3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from human TNINI3.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P19429
Buffer	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.