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Phospho-SREBP-1 (Ser439) Antibody detects endogenous levels of SREBP-1 only when phosphorylated at Serine 439. This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosesynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum.

Target	SREBP-1 (pS439)
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	A synthesized peptide derived from human SREBP-1 around the phosphorylation site of Serine 439.
Purification	Immunogen affinity purified.
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	122 kDa
Swiss Prot	P36956
Buffer	Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.