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 ITGB7 Antibody abx028592|产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    ITGB7 Antibody
    品牌:
    货号:abx028592
    规格:80 μl
    货期:

    ITGB7 Antibody

    商品详情 参考文献 相关资料
    Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    Target ITGB7
    Reactivity Human
    Host Rabbit
    Clonality Polyclonal
    Tested Applications WB
    Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
    Immunogen Human ITGB7.
    Purification Peptide Affinity Purified Rabbit Polyclonal Antibody.
    Isotype IgG
    Conjugation Unconjugated
    Specificity This ITGB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the C-terminal region of human ITGB7.
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Swiss Prot P26010
    Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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