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CYP3A4 Antibody abx000048|产品详情|进口橙子视频旧款采购网




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    CYP3A4 Antibody
    品牌:
    货号:abx000048
    规格:10 μl
    货期:

    CYP3A4 Antibody

    商品详情 参考文献 相关资料
    CYP3A4 Antibody is a Mouse Monoclonal antibody against CYP3A4. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Target CYP3A4
    Reactivity Human
    Origin Human
    Host Mouse
    Clonality Monoclonal
    Tested Applications WB
    Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
    Immunogen Recombinant protein of human CYP3A4.
    Purification Affinity purified.
    Form Liquid
    Isotype IgG
    Conjugation Unconjugated
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Molecular Weight Calculated MW: 57 kDa
    Observed MW: 50 kDa
    Swiss Prot P08684
    GeneID 1576
    Gene Symbol CYP3A4
    OMIM 124010
    HGNC 2637
    Ensembl ENSG00000160868
    Concentration > 1 mg/ml
    Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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