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This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain.Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus.This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Target	KEAP1
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA, WB, IHC, FCM
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. coli.
Purification	Purified antibody
Isotype	IgG1
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	69.7 kDa
Concentration	1.0 mg/ml
Buffer	PBS with 0.05% sodium azide and 0.5% protein stabilizer.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.