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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. This antibody is supplied as crude ascites.

Target	CDKN1C
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human CDKN1C.
Purification	Mouse Monoclonal Antibody (Mab) supplied as crude ascites.
Isotype	IgM
Conjugation	Unconjugated
Specificity	This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P49918
Buffer	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.