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DKK3 Antibody abx028489|产品详情|进口橙子视频旧款采购网




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    DKK3 Antibody
    品牌:Abbexa
    货号:abx028489
    规格:80 μl
    货期:

    DKK3 Antibody

    商品详情 参考文献 相关资料
    DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.

    Target DKK3
    Reactivity Human
    Host Rabbit
    Clonality Polyclonal
    Tested Applications WB
    Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
    Immunogen Human DKK3.
    Purification Purified Rabbit Polyclonal Antibody.
    Isotype IgG
    Conjugation Unconjugated
    Specificity This DKK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human DKK3.
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Swiss Prot Q9UBP4
    NCBI Accession NP_001018067.1 NP_037385.2 NP_056965.3
    Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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