Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop IRPAI-P1NBD|产品详情|进口橙子视频旧款采购网

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Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop

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Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop

品牌：Innovative Research

货号：IRPAI-P1NBD

规格：0.5mg

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Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop

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Rat PAI-1 NBD labeled at the scissile bond of the reactive center loop

P1'-NBD rat PAI-1 was created by mutagenesis of the methionine residue (Met348) at the P1-P1' scissile bond to cysteine. This provides a free thiol group for labeling with NBD, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-NBD PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase. This unique product is an ideal reagent for researchers studying PAI-1 behavior in rat models.

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