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ProTx-II (0.1mg vial)

品牌：Peptides International

货号：PTX-4450-s

规格：1ea

货期：

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ProTx-II (0.1mg vial)

商品详情参考文献相关资料

Product Code: PTX-4450-s
Synonyms/Product Alternate Names: Tyr-Cys-Gln-Lys-Trp-Met-Trp-Thr-Cys-Asp-Ser-Glu-Arg-Lys-Cys-Cys-Glu-Gly-Met-Val-Cys-Arg-Leu-Trp-Cys-Lys-Lys-Lys-Leu-Trp; ProTx2, ProTx-2

Na+ Channel (Especially Nav1.7) / Ca2+ Ion Channel Blocker (Gating Modifier)
A tarantula venom-peptide whose sequence is derived from Thrixopelma pruriens.
Storage Conditions: -20 °C
Molecular Weight: 3826.6
Molecular Formula: C₁₆₈H₂₅₀N₄₆O₄₁S₈
Disulfide Bonds: (Disulfide Bonds between Cys²- Cys¹⁶, Cys⁹- Cys²¹, and Cys¹⁵- Cys²⁵)
One-Letter Code:
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW

R.E. Middleton, V.A. Warren, R.L. Kraus, J.C. Hwang, C.J. Liu, G. Dai, R.M. Brochu, M.G. Kohler, Y.-D. Gao, V.M. Garsky, M.J. Bogusky, J.T. Mehl, C.J. Cohen, and M.M. Smith, Biochemistry, 41,14734 (2002).(Original)
J.J. Smith, T.R. Cummins, S. Alphy, and K.M. Blumenthal, J. Biol. Chem., 282, 12687 (2007). (Pharmacol.; Novel Toxin Coupled to Na_V Activation)
B.T. Priest, K.M. Blumenthal, J.J. Smith, V.A. Warren, and M.M. Smith, Toxicon, 49,194 (2007). (Review)