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Anti-Myc (Ab-358) Antibody

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Anti-Myc (Ab-358) Antibody

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Overview	Print Version
Product Name	Anti-Myc (Ab-358) Antibody
Description	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocations of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Subtype	polyclonal
Application	WB, IHC
Raised In	rabbit
Specificity	Myc (Ab-358) antibody detects endogenous levels of total Myc protein.
Immunogen	The antiserum was produced against synthesized non-phosphopeptide derived from human Myc around the phosphorylation site of threonine 358 (R-R-TP-H-N).
Guarantee	abm guarantees that all our Anti-Myc (Ab-358) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation	Liquid
Quantity	100 μg
Clone	N/A
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1µg/ul
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Species Reactivity	human, mouse, rat
Anti-Myc (Ab-358) Antibody Images

Specific References
Y021035 has been referenced in 1 publication. Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.