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*Please inquire the availability for this product. Demeclocycline, a chlortetracycline analogue produced by a mutagenised strain of Streptomyces aureofaciens, was first isolated in 1957. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Demeclocycline has been extensively cited in the literature with over 800 references relating almost exclusively to in vivo use.

Additional Information

Synonyms	6-Demethylchlotetracycline, DMCT, 7-Chloro-6-demethyltetracycline, Ledermycin, RP 10192
Product #	D-2483
CAS #	127-33-3
Formula	C21H21ClN2O8
MW	468.9
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Demeclocycline shows broad spectrum antibacterial and antiprotozoan activityÂÂ

Additional Information

MDL Number	MFCD00864922
InChI	InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14-,15-,21-/m0/s1
SMILES	CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O