2'-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor |产品详情|进口橙子视频旧款采购网

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2'-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor

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2'-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor

品牌：AG Scientific

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规格：100 mg

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CAS:10356-76-0Formula:C9H12FN3O4MW:245.21Appearance:WhitesolidPurity:98%byTLCNMR(Conforms)

商品详情参考文献相关资料

2'-Deoxy-5-fluorocytidine is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5'-Azacytidine and decitabine, 2-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.

Additional Information

Synonyms	FCDR; NSC-48006; FdCyd
Product #	D-2631
CAS #	10356-76-0
Chemical Name	5-Fluoro-2'deoxycytidine
Formula	C₉H₁₂FN₃O₄
MW	245.21
Appearance	White solid
Purity	98% by TLC NMR (Conforms)
Solubility	Soluble in DMSO (up to 20 mg/ml).
Storage Temp	-20°