1-Deoxynojirimycin |产品详情|进口橙子视频旧款采购网

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1-Deoxynojirimycin

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:19130-96-2Formula:C6H13NO4MW:163.2Appearance:WhiteCrystallineSolidPurity:98%

商品详情参考文献相关资料

1-deoxynojirimycin (DNJ), also called duvoglustat or moranolin. 1-deoxynojirimycin derived from Mulberry leaves, is a potent inhibitor of intestinal α-glycosidases, which acts as an antihyperglycemic agent by slowing the rate of carbohydrate degradation to monosaccharides. Deoxynojirimycin inhibits α-glucosidase I and II. Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step. May be used to produce an affinity ligand for purifying glucosidase 1. Deoxynojirimycin was used to inhibit ER glucosidases I and II allowing for the discovery of a second mechanism for deglucosylation of N-linked oligosaccharides in PhaR1.7, a mouse lymphoma cell line.

Additional Information

Synonyms	dNM, Duvoglustat, moranolin
Product #	D-1157
CAS #	19130-96-2
Chemical Name	5-AMINO-1,5-DIDEOXY-D-GLUCOPYRANOSE
Formula	C₆H₁₃NO₄
MW	163.2
Appearance	White Crystalline Solid
Purity	98%
Solubility	Soluble in DMSO. Dilute with distilled water or buffer; also soluble in phosphate buffer, pH 7.5.
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	An alpha-glucosidase inhibitor with antiviral action in anti-HIV activity

Additional Information

MDL Number	MFCD00063474
ChemACX	X1794671-7
InChI	InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
SMILES	C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O

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