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SR9243, LXR inverse agonist |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    SR9243, LXR inverse agonist
    品牌:AG Scientific
    货号:
    规格:25 mg
    货期:

    CAS:1613028-81-1Formula:C31H32BrNO4S2MW:626.62Appearance:WhitesolidPurity:>98%byHPLCNMR(Conforms)

    商品详情 参考文献 相关资料

    SR9243 (1613028-81-1) is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50= 18 nM). SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.

    Additional Information

    Product #S-3335
    CAS #1613028-81-1
    Chemical NameN-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3Õ-(methylsulfonyl)[1,1Õ-biphenyl]-4-yl]methyl]-benzenesulfonamide
    FormulaC31H32BrNO4S2
    MW626.62
    AppearanceWhite solid
    Purity>98% by HPLC NMR (Conforms)
    SolubilitySoluble in DMSO (greater than 25 mg/ml)
    Storage Temp-20°C (des.)

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