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Anisomycin, Flagecidin

品牌：AG Scientific

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规格：10 mg

货期：

应用：

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CAS:22862-76-6Formula:C14H19NO4MW:265.31Appearance:WhitecrystallinepowderPurity:>98%byHPLC

商品详情参考文献相关资料

Anisomycin is an antibiotic produced by Streptomyces griseolus. It functions by inhibiting protein synthesis in certain eukaryotic cells. Anisomycin inhibits peptidyl transferase activity in the 60s subunit of the 80s ribosome. It also increases the phosphorylation of p70 S6 kinase α.

Anisomycin has been shown to promote apoptosis in promyelocytic leukemia cells, Jurkat cells, ventricular monocytes, and colon adenocarcinoma cells. Additionally, anisomycin is a JNK agonist and activates MAP kinases. It is used in Martin-Lewis Medium to inhibit Candida Albicans and aid in the identification of N.gonorrhea. Anisomycin or Flagecidin is also an anti-protozoal agent.

Additional Information

Synonyms	Flagecidin, SA 3097C1, PA 106, Anhydroscopin A, NSC 76712, (2S,3R,4R)-2-(4-methoxybenzyl)-4-hydroxypyrrolidin-3-yl acetate
Product #	A-1049
CAS #	22862-76-6
Chemical Name	2-[(4-METHOXYPHENYL)METHYL]-3,4-PYRROLIDINEDIOL 3-ACETATE
Formula	C₁₄H₁₉NO₄
MW	265.31
Appearance	White crystalline powder
Purity	>98% by HPLC
Solubility	Soluble in DMSO
Melting Point	139-142°C
Storage Temp	Store desiccated at +4° C
Therapeutic Area	Psychological Disorders, Infectious Diseases

Additional Information

Merck Index	13.673.2001
MDL Number	MFCD00077650
ChemACX	X1000859-4
InChI	InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m0/s1
SMILES	CC(=O)O[C@H]1[C@@H](CN[C@H]1Cc2ccc(cc2)OC)O