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Phosphoenolpyruvate, Monopotassium Salt

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CAS:4265-07-0Formula:C3H4O6P.KMW:206.1g.mol-1Appearance:Whitecrystals

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A Substrate for the detection of carboxylase. An enzyme substrate for glycolysis and gluconeogenesis pathways; metabolized to pyruvate by pyruvate kinase during glycolysis; formed from phosphoenolpyruvate carboxykinase-catalyzed by oxaloacetate decarboxylation during gluconeogenesis

Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.