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*Please inquire the availability for this product. Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.

Additional Information

Synonyms	5-Oxomilbemycin A3 oxime
Product #	M-2587
CAS #	114177-14-9
Formula	C31H43NO7
MW	541.7
Appearance	White solid
Purity	>99% by HPLC
Solubility	Soluble in ethanol, methanol, DMSO, DMF, and water (poorly)
Storage Temp	-20°C
Use	The minor component of the anti-parasitic product milbemycin oxime

Additional Information

MDL Number	MFCD21363714
InChI	InChI=1S/C31H43NO7/c1-18-7-6-8-23-17-36-28-27(32-35)21(4)14-26(31(23,28)34)29(33)37-25-15-24(10-9-19(2)13-18)39-30(16-25)12-11-20(3)22(5)38-30/h6-9,14,18,20,22,24-26,28,34-35H,10-13,15-17H2,1-5H3/b7-6+,19-9+,23-8+,32-27?/t18-,20-,22+,24+,25?,26?,28+,30-,31+/m0/s1
SMILES	C[C@H]1CC[C@]2(CC3C[C@H](O2)C/C=C(/C[C@H](/C=C/C=C/4\CO[C@H]5[C@@]4(C(C=C(C5=NO)C)C(=O)O3)O)C)\C)O[C@@H]1C