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Chk2 Inhibitor |产品详情|进口橙子视频旧款采购网




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    订购信息
    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Chk2 Inhibitor
    品牌:AG Scientific
    货号:
    规格:1 mg
    货期:

    Formula:C20H14CIN3O2MW:363.8Appearance:PaleyellowSolidPurity:98%byHPLC

    商品详情 参考文献 相关资料
    A cell-permeable, potent, and ATP-competitive inhibitor of Chk2 (checkpoint kinase 2; IC= 15 nM; Ki = 37 nM). Displays ~1,000-fold greater selectivity for Chk2 compared to Cdk1/cyclin B and CK1 (IC= 12 M and 17 M, respectively) and only weakly affects the activities of a panel of 31 kinases ( 25% inhibition at 10 M), including Chk1. Shown to rescue both peripheral CD4+ and CD8+ T-cells from -irradiation-induced apoptosis with an ECof 3 M and 7.6 M, respectively.

    Additional Information

    Synonyms2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
    Product #C-2264
    Chemical Name2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
    FormulaC20H14CIN3O2
    MW363.8
    AppearancePale yellow Solid
    Purity98% by HPLC
    SolubilitySoluble in DMSO (10 mg/ml)
    Storage Temp+4°C

    Additional Information

    MDL NumberMFCD08276917
    ChemACXX1835816-4
    InChIInChI=1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
    SMILESC1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl
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