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Chlorothricin

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:34707-92-1Formula:C50H63CIO16MW:955.5Appearance:WhitePowderPurity:99%byHPLC

商品详情参考文献相关资料

The tetronic acid, chlorothricin is an unusual macrocyclic antibiotic from Streptomyces sp. Related to kijanimicin, sccharocarcins, tetrocarcin and versipelostatin. It shows inhibitory activity against cholesterol biosesynthesis from mevalsonate and inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azobacter vinelandii.

Additional Information

Synonyms	Antibiotic 818A
Product #	C-1400
CAS #	34707-92-1
Chemical Name	(1S,3R,6R,7E,13R,16S,17S,21R,22R)-17-((4-O-[3-O-(3-CHLORO-6-METHOXY-2-METHYLBENZOYL)-2,6-DIDEOXY-Β-D-ARABINO-HEXOPYRANOSYL]-2,6-DIDEOXY-Β-D-ARABINO-HEXOPYRANOSYL)OXY)-28-HYDROXY-3,22-DIMETHYL-23 ,26-DIOXO-24,27-DIOXAPENTACYCLO[23.2.1.01,6.013,22.016,21]OC
Formula	C₅₀H₆₃CIO₁₆
MW	955.5
Appearance	White Powder
Purity	99% by HPLC
Solubility	Readily Soluble in Water
Storage Temp	-20°C
Use	A spirotetronic acid antibiotic inhibitor of pyruvate carboxylase

Additional Information

MDL Number	MFCD08062298
ChemACX	X6952241-8
InChI	InChI=1S/C50H63ClO16/c1-24-23-50-29(20-31(24)45(55)56)13-10-8-7-9-12-28-16-17-30-32(49(28,5)48(59)66-43(44(50)54)47(58)67-50)14-11-15-35(30)63-38-21-34(52)42(27(4)62-38)65-39-22-37(41(53)26(3)61-39)64-46(57)40-25(2)33(51)18-19-36(40)60-6/h10,13,16-20,24,26-30,32,34-35,37-39,41-42,52-54H,7-9,11-12,14-15,21-23H2,1-6H3,(H,55,56)/b13-10+/t24-,26-,27-,28-,29-,30+,32-,34-,35+,37-,38+,39+,41-,42-,49-,50+/m1/s1
SMILES	Cc1c(ccc(c1C(=O)O[C@@H]2C[C@@H](O[C@@H]([C@H]2O)C)O[C@@H]3[C@H](O[C@H](C[C@H]3O)O[C@H]4CCC[C@@H]5[C@@H]4C=C[C@@H]6[C@]5(C(=O)OC7=C([C@@]8(C[C@H](C(=C[C@H]8/C=C/CCCC6)C(=O)O)C)OC7=O)O)C)C)OC)Cl

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