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Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC= 8.8M for human PRMT1 and 3.0M for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) . Also acts as a HIV-1 RT polymerase inhibitor (IC= 5.0M).

Additional Information

Synonyms	Arginine N-methyltransferase inhibitor-1
Product #	A-2184
Chemical Name	Arginine N-methyltransferase inhibitor-1
Formula	C21H12N2O9S2Na4
MW	592.42
Appearance	Brown Solid
Purity	98% by NMR
Solubility	DMSO or Ethanol or water
Storage Temp	-20°C

Additional Information

InChI	InChI=1S/C21H16N2O9S2.4Na/c24-19-9-15(33(27,28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30,31)32;;;;/h1-10,24-25H,(H2,22,23,26)(H,27,28,29)(H,30,31,32);;;;/q;4*+1/p-4
SMILES	O=C(NC1=CC(C=C(S(=O)([O-])=O)C=C2[O-])=C2C=C1)NC3=CC4=C(C([O-])=CC(S(=O)([O-])=O)=C4)C=C3.[Na+].[Na+].[Na+].[Na+]