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Pifithrin-Alpha hydrobromide |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
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    Pifithrin-Alpha hydrobromide
    品牌:AG Scientific
    货号:
    规格:10 mg
    货期:

    CAS:63208-82-2Formula:C16H18N2OS.BrHMW:367.3Appearance:Off-WhiteSolidPurity:98%

    商品详情 参考文献 相关资料

    Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53 dependent transcriptional activation and apoptosis.p53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition.p53 Down-Regulates Phosphatase and Tensin Homologue Deleted on Chromosome 10 Protein Stability Partially through Caspase-Mediated Degradation in Cells with Proteasome Dysfunction.Histone Deacetylase InhibitorMediated Radiosesensitization of Human Cancer Cells: Class Differences and the Potential Influence of p53.Early Single Cell Bifurcation of Pro- and Antiapoptotic States during Oxidative Stress.

    Additional Information

    Synonyms1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
    Product #P-1177
    CAS #63208-82-2
    Chemical Name1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
    FormulaC16 H18 N2 O S . Br H
    MW367.3
    AppearanceOff-White Solid
    Purity98%
    SolubilitySoluble in DMSO, DMF, Methanol.
    Melting Point192.1-192.5 °C
    Storage Temp-20°C
    Therapeutic AreaOncological Disorders
    UseAn inhibitor of p53 that reversibly blocks p53 dependent transcriptional activation and apoptosis

    Additional Information

    MDL NumberMFCD00417851
    ChemACXX1343322-2
    InChIInChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
    SMILESCc1ccc(cc1)C(=O)Cn2c3c(sc2=N)CCCC3.Br
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