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Ponasterone A | CAS [13408-56-5]| PONASTERONE A USE OF INSECT GENE INDUCER TO E |产品详情|进口橙子视频旧款采购网




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    Ponasterone A | CAS [13408-56-5]| PONASTERONE A USE OF INSECT GENE INDUCER TO E
    品牌:AG Scientific
    货号:
    规格:1 mg
    货期:

    CAS:13408-56-5Formula:C27H44O6MW:464.6Appearance:OffWhitePowderPurity:98%

    商品详情 参考文献 相关资料

    Ponasterone A is an Insect steroid hormone involved in regulating metamorphosis. It is an analog of ecdysone A and a member of the ecdysteroid family with similar properties to muristerone A. It is a functional, reliable and economical substitute for muristerone A as an inducer for the ecdysone-inducible mammalian expression system.

    Ponasterone A is a highly bioactive ligand that has demonstrated sustained release and transgene expression in vivo. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly. It inhibits cell growth and increased cell number at the G1 phase. Treatment of cells with the synthetic ecdysone analog ponasterone A, induced expression of GFP-MKK7(3E) and resulted in sustained activation of endogenous JNK, but neither of the other endogenous MAPK's, ERK orp38.

     

    Additional Information

    SynonymsPon A
    Product #P-1083
    CAS #13408-56-5
    Chemical Name25-Deoxyecdysteronell25-Deoxy-20-hydroxyecdysonell2b,3b,14a,20R,22R-Pentahydroxy-5b-cholest-7-en-6-one
    FormulaC27H44O6
    MW464.6
    AppearanceOff White Powder
    Purity98%
    SolubilitySoluble in acetic acid, 100% ethanol, methanol or DMSO. Insoluble in water.
    Storage TempStore desiccated at -20°C.

    Additional Information

    Merck Index14 : 7588
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