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Necrosis Inhibitor-5 |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Necrosis Inhibitor-5
    品牌:AG Scientific
    货号:
    规格:1 mg
    货期:

    Formula:C25H31NO3S.2CH4O3SMW:645.83Appearance:GrayPowderPurity:96%

    商品详情 参考文献 相关资料

    Cell permeable necrosis inhibitor with antioxidant activity. It localizes mostly in mitochondria. Selectively blocks oxidative stress-induced necrotic death (0.1M Necrosis Inhibitor 5, prevented 50% cell death in H9C2 cells exposed to 400M t-BuOOH for 2 hours LDH assay used). Does not protect against staurosporine or Etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro, as well as, CCL4- induced acute liver and chronic liver fibrosis in rodent models.in vitro Cell-based assays: Cold Stress, Hypoxia, Oxidative Stress.in vivo Necrosis Animal Models for Liver disease: DILI (Acetaminophen, CCL4), CCL4 induced Liver Fibrosis/Cirrhosis.Ischemia Reperfusion Injury: Stroke, Myocardial Infarction, Acute Pancreatitis Acute Tubular Necrosis.Cell Media: Cell Therapy

    Additional Information

    SynonymsNecrox-5
    Product #N-1223
    Chemical Name[[5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine
    FormulaC25H31NO3S.2CH4O3S
    MW645.83
    AppearanceGray Powder
    Purity96%
    SolubilitySoluble in DMSO (10mg/ml) or distilled water (10mg/ml)
    Storage Temp+4°C
    Therapeutic AreaCardiological Disorders
    UseUse in Stroke, Myocardial Infarction

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