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p300/CBP inhibitor, C-646 |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    p300/CBP inhibitor, C-646
    品牌:AG Scientific
    货号:
    规格:1 mg
    货期:

    CAS:328968-36-1Formula:C24H19N3O6MW:445.42Appearance:RedSolidPurity:98%byNMR

    商品详情 参考文献 相关资料

    Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (K = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (10%). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.

    Additional Information

    Synonyms(E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid; C646, p300/CBP Inhibitor
    Product #C-2212
    CAS #328968-36-1
    Chemical Name(E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
    FormulaC24H19N3O6
    MW445.42
    AppearanceRed Solid
    Purity98% by NMR
    SolubilityDMSO (25 mM)
    Storage Temp-20°C
    UseC646 is a competitive histone acetyltransferase (HAT) p300/CBP inhibitor use in cancer

    Additional Information

    MDL NumberMFCD01784780
    ChemACXX3304905-5
    InChIInChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12-
    SMILESCc1cc(c(cc1C)[N+](=O)[O-])c2ccc(o2)/C=C3/C(=NN(C3=O)c4ccc(cc4)C(=O)O)C
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