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Lovastatin |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
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    Lovastatin
    品牌:AG Scientific
    货号:
    规格:Inquire
    货期:

    CAS:75330-75-5Formula:C24H36O5MW:404.55Appearance:WhiteSolidPurity:>98%byHPLC

    商品详情 参考文献 相关资料

    HMG-CoA reductase inhibitor. Lovastatin, Mevinolin, MK-803, inhibits HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase). Lovastatin also inhibits MAP kinase and p21ras activation. General transcription factor specified global gene regulation in archaea. Determination of Lovastatin Hydroxy Acid in Female B6C3F1 Mouse Serum. A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. Crosstalk between cytosolic and plastidial pathways of isoprenoid biosesynthesis in Arabidopsis thaliana. Transcytotic Efflux from Early Endosomes Is Dependent on Cholesterol and Glycosphingolipids in Polarized Hepatic Cells. Statin Compounds Reduce Human Immunodeficiency Virus Type 1 Replication by Preventing the Interaction between Virion-Associated Host Intercellular Adhesion Molecule 1 and Its Natural Cell Surface Ligand LFA-1. Statin Inhibition of Fc ReceptorMediated Phagocytosis by Macrophages Is Modulated by Cell Activation and Cholesterol. PAF-receptor antagonists, lovastatin, and the PTK inhibitor genistein inhibit H2O2 secretion by macrophages cultured on oxidized-LDL matrices. Statins Activate AMP-Activated Protein Kinase In Vitro and In Vivo. Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon.

    Additional Information

    SynonymsMevinolin, MK-803, 6-a-Methylcompactin, Monacolin K
    Product #L-1043
    CAS #75330-75-5
    Chemical Name6-a-Methylcompactin
    FormulaC24H36O5
    MW404.55
    AppearanceWhite Solid
    Purity>98% by HPLC
    SolubilitySoluble in ethanol, methanol, DMF or DMSO. Limited water solubility
    Melting Point175.4 °C
    Storage Temp-20°C
    Therapeutic AreaCardiological Disorders, Metabolic Disorders
    UseLovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) to reduce risk of cardiovascular disease.

    Additional Information

    Merck Index13.5608.2001
    MDL NumberMFCD00072164
    ChemACXX1000555-1
    InChIInChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
    SMILESCC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C
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