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GW501516

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:317318-70-0Formula:C21H18F3NO3S2MW:453.5Appearance:Whitetooff-whiteSolidPurity:98%byHPLC

商品详情参考文献相关资料

A selective agonist for PPAR (peroxisome proliferator-activated receptor) (EC= 1. 1 nM), displaying 1000-fold selectivity over the other human subtypes. In macrophages, fibroblasts, and intestinal cells, GW501516 increases expression of the reverse cholesterol transporter ATP-binding cassette A1 and induces apolipoprotein A1-specific cholesterol efflux.

Additional Information

Synonyms	(2-Methyl-4-(((4-methyl-2-(4-trifluoromethylphenyl)-1,3-thiazol-5-yl)methyl)sulfanyl)phenoxy)acetic acid
Product #	G-2348
CAS #	317318-70-0
Chemical Name	(2-Methyl-4-(((4-methyl-2-(4-trifluoromethylphenyl)-1,3-thiazol-5-yl)methyl)sulfanyl)phenoxy)acetic acid
Formula	C₂₁H₁₈F₃NO₃S₂
MW	453.5
Appearance	White to off-white Solid
Purity	98% by HPLC
Solubility	DMSO (50 mg/ml) or EtOH (12 mg/ml)
Storage Temp	-20°C
Therapeutic Area	Endocrinological Disorders
Use	A selective and potent PPARβ agonist

Additional Information

MDL Number	MFCD09033000
ChemACX	X1463059-2
InChI	InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)
SMILES	CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)OCC(=O)O

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