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*Please inquire the availability for this product. Doxycycline is a semi-synthetic tetracycline prepared by hydrogenolysis of oxytetracycline to remove the 6-hydroxy group. Although the synthesis was reported in 1958, it was not released for use until 1967. Doxycycline, together with minocycline, is regarded as a ‘third generation’ tetracycline largely replacing the analogues and pro-drugs produced in the early 1960s for mainstream antibiotic applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Doxycycline has been extensively cited in the literature with over 10,000 references.

Additional Information

Synonyms	6- Deoxy-5-hydroxytetracycline, 6-Deoxyoxytetracycline, Doxytetracycline, GS 3065, Hydramycin, Medeomycin, Vibramycin
Product #	D-2543
CAS #	564-25-0
Formula	C22H24N2O8
MW	444.4
Appearance	Yellow to orange solid
Purity	>98% by HPLC
Melting Point	201 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Doxycycline is used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, rickettsial infections

Additional Information

MDL Number	MFCD00800994
InChI	InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1
SMILES	C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=C(C(=O)[C@]3(C(=C2C(=O)C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O