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Anti-FANCC Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-FANCC Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-FANCC Antibody

    商品详情 参考文献 相关资料
    Name: Anti-FANCC Antibody
    See all FANCC primary antibodies
    Description: Rabbit polyclonal antibody to FANCC
    Specificity: The antibody detects endogenous level of total FANCC protein.
    Applications: WB, IHC, IF
    Reactivity: Human
    Immunogen: Recombinant protein of human FANCC.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antibodies were purified by affinity purification using immunogen.
    Concentration: 1.0mg / ml
    Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20?C
    Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    Tissue Specificity: Ubiquitous.
    Involvement in Disease: Fanconi anemia complementation group C: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
    Cellular locations: Nucleus. Cytoplasm.

    The major form is nuclear. The minor form is cytoplasmic.
    Database Links:
  • Entrez Gene: 2176?Human
  • Omim: 613899?Human
  • SwissProt: Q00597?Human
  • Unigene: 494529?Human
  • Synonyms:
  • bA80I15.1 Antibody
  • FA 3 Antibody
  • FA3 Antibody
  • FAC Antibody
  • FACC Antibody
  • FANCC Antibody
  • FANCC_HUMAN Antibody
  • Fanconi anemia complementation group C Antibody
  • Fanconi anemia complementation group C protein Antibody
  • Fanconi anemia group C protein Antibody
  • Fanconi pancytopenia type 3 Antibody
  • FLJ14675 Antibody
  • Protein FACC Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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