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Anti-FADS1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-FADS1 Antibody

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Name:	Anti-FADS1 Antibody See all FADS1 primary antibodies
Description:	Rabbit polyclonal antibody to FADS1
Specificity:	The antibody detects endogenous levels of total FADS1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human fatty acid desaturase 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.8mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosesynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.
Tissue Specificity:	Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.
Sequence Similarities:	Belongs to the fatty acid desaturase type 1 family.
Cellular locations:	Endoplasmic reticulum membrane. Mitochondrion.
Database Links:	Entrez Gene: 3992?Human Omim: 606148?Human SwissProt: O60427?Human Unigene: 503546?Human
Synonyms:	D5D Antibody Delta 5 desaturase Antibody Delta 5 fatty acid desaturase Antibody Delta(5) desaturase Antibody Delta(5) fatty acid desaturase Antibody Delta-5 desaturase Antibody FADS1 Antibody FADS1_HUMAN Antibody FADS6 Antibody FADSD5 Antibody Fatty acid desaturase 1 Antibody FLJ38956 Antibody Linoleoyl CoA desaturase (delta 6 desaturase) like 1 Antibody LLCDL1 Antibody TU12 Antibody
Information:	Target information shown above is from the UniProt Consortium.