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Anti-EPS15L1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-EPS15L1 Antibody

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Name:	Anti-EPS15L1 Antibody See all EPS15L1 primary antibodies
Description:	Rabbit polyclonal antibody to EPS15L1
Specificity:	The antibody detects endogenous levels of total EPS15L1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human epidermal growth factor receptor pathway substrate 15-like 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.4mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Post-Translational Modification:	Phosphorylated on tyrosine residues by EGFR.
Cellular locations:	Cell membrane. Nucleus. Membrane > Coated pit. Localized to plasma membrane coated pits.
Database Links:	Entrez Gene: 58513?Human Omim: 600051?Human SwissProt: Q9UBC2?Human Unigene: 654639?Human Unigene: 744842?Human
Synonyms:	EP15R_HUMAN Antibody epidermal growth factor receptor pathway substrate 15- ike 1 Antibody Epidermal growth factor receptor substrate 15 like 1 Antibody Epidermal growth factor receptor substrate 15-like 1 Antibody epidermal growth factor receptor substrate EPS15R Antibody Eps15 related protein Antibody Eps15-related protein Antibody EPS15L1 Antibody EPS15R Antibody
Information:	Target information shown above is from the UniProt Consortium.