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Anti-ENC-2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-ENC-2 Antibody

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Name:	Anti-ENC-2 Antibody See all ENC-2 primary antibodies
Description:	Chicken polyclonal antibody to ENC-2
Applications:	E, WB, ICC
Reactivity:	Human
Immunogen:	Raised against a 14 amino acid peptide near the center of human ENC-2.
Host:	Chicken
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.
Database Links:	Entrez Gene: 64410 Human SwissProt: Q9H0H3 Human Unigene: 498371 Human
Synonyms:	2810402K13Rik Antibody BC027373 Antibody Ectoderm neural cortex protein 2 Antibody Ectoderm-neural cortex protein 2 Antibody ENC 2 Antibody ENC-2 Antibody ENC2 Antibody ENC2_HUMAN Antibody FLJ12587 Antibody FLJ45015 Antibody Kelch like protein 25 Antibody Kelch-like protein 25 Antibody KLHL25 Antibody MGC116251 Antibody MGC36331 Antibody RGD1310815 Antibody
Information:	Target information shown above is from the UniProt Consortium.