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Anti-DUSP4 Antibody

品牌：Antibodies

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规格：50µl

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Anti-DUSP4 Antibody

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Name:	Anti-DUSP4 Antibody See all DUSP4 primary antibodies
Description:	Rabbit polyclonal antibody to DUSP4
Specificity:	The antibody detects endogenous level of total DUSP4 protein.
Applications:	E, WB, IHC
Dilutions:	ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:150
Reactivity:	Human, Mouse
Immunogen:	Fusion protein corresponding to a region derived from 197-394 amino acids of human dual specificity phosphatase 4
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Predicted MW:	43kd
Formulation:	Supplied at 1.2mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Function:	Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Sequence Similarities:	Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Post-Translational Modification:	Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
Cellular locations:	Nucleus.
Database Links:	Entrez Gene: 1846?Human Entrez Gene: 319520?Mouse Omim: 602747?Human SwissProt: Q13115?Human SwissProt: Q8BFV3?Mouse Unigene: 417962?Human Unigene: 170276?Mouse Unigene: 392187?Mouse
Synonyms:	Dual specificity phosphatase 4 Antibody Dual specificity protein phosphatase 4 Antibody Dual specificity protein phosphatase hVH2 Antibody DUS4_HUMAN Antibody DUSP 4 Antibody DUSP4 Antibody HVH 2 Antibody HVH2 Antibody MAP kinase phosphatase 2 Antibody Mitogen activated protein kinase phosphatase 2 Antibody Mitogen-activated protein kinase phosphatase 2 Antibody MKP 2 Antibody MKP-2 Antibody MKP2 Antibody Serine/threonine specific protein phosphatase Antibody TYP Antibody Typ1 Antibody VH 2 Antibody VH1 homologous phosphatase 2 Antibody VH2 Antibody
Information:	Target information shown above is from the UniProt Consortium.