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Anti-CAMTA1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CAMTA1 Antibody

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Name:	Anti-CAMTA1 Antibody See all CAMTA1 primary antibodies
Description:	Rabbit polyclonal antibody to CAMTA1
Specificity:	The antibody detects endogenous levels of total CAMTA1 protein.
Applications:	IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to residues near the C terminal of human calmodulin binding transcription activator 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.2mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Transcriptional activator. May act as a tumor suppressor.
Tissue Specificity:	Normally expressed in non-neoplastic ***** central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astrocytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. Expressed in heart and kidney.
Involvement in Disease:	Cerebellar ataxia, non-progressive, with mental retardation: A neurodevelopmental disorder characterized by mildly delayed psychomotor development, early onset of cerebellar ataxia, and intellectual disability later in childhood and ***** life. Other features may include neonatal hypotonia, dysarthria, and dysmetria. Brain imaging in some patients shows cerebellar atrophy. Dysmorphic facial features are variable.
Sequence Similarities:	Belongs to the CAMTA family.
Cellular locations:	Nucleus. Cytoplasm.
Database Links:	Entrez Gene: 23261?Human Entrez Gene: 100072?Mouse Omim: 611501?Human SwissProt: Q9Y6Y1?Human SwissProt: A2A898?Mouse Unigene: 397705?Human Unigene: 671020?Human Unigene: 318846?Mouse
Synonyms:	Calmodulin-binding transcription activator 1 Antibody CAMTA1 Antibody CANPMR Antibody CMTA1 Antibody KIAA0833 Antibody
Information:	Target information shown above is from the UniProt Consortium.