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Anti-Bim Antibody

品牌：Antibodies

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规格：100µl

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Anti-Bim Antibody

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Name:	Anti-Bim Antibody See all Bim primary antibodies
Description:	Rabbit polyclonal antibody to Bim
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a peptide corresponding to amino acids near the center of human Bim. The sequence is identical to that of mouse and differs from that of rat by one amino acid.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Induces apoptosis and anoikis.
Tissue Specificity:	Widely expressed.
Sequence Similarities:	Belongs to the Bcl-2 family.
Post-Translational Modification:	Phosphorylation at Ser-65 by MAPK1/MAPK3 leads interaction with TRIM2 and ubiquitination, followed by proteasomal degradation. Deubiquitination catalyzed by USP27X stabilizes the protein.
Cellular locations:	Membrane. Mitochondrion. Associated with intracytoplasmic membranes.
Database Links:	Entrez Gene: 10018?Human Entrez Gene: 12125?Mouse Entrez Gene: 64547?Rat Omim: 603827?Human SwissProt: O43521?Human SwissProt: O54918?Mouse SwissProt: O88498?Rat Unigene: 469658?Human Unigene: 141083?Mouse Unigene: 453214?Mouse Unigene: 82709?Rat
Synonyms:	BCL2 like 11 Antibody B2L11_HUMAN Antibody BAM Antibody Bcl 2 interacting protein Bim Antibody Bcl 2 related ovarian death agonist Antibody Bcl-2-like protein 11 Antibody BCL2 interacting mediator of cell death Antibody BCL2 like 11 (apoptosis facilitator) Antibody BCL2 like protein 11 Antibody Bcl2-interacting mediator of cell death Antibody Bcl2-L-11 Antibody Bcl2l11 Antibody Bim Antibody BIM alpha6 Antibody BIM beta6 Antibody BIM beta7 Antibody BimEL Antibody BimL Antibody BOD Antibody
Information:	Target information shown above is from the UniProt Consortium.