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Anti-ATG4B Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-ATG4B Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-ATG4B Antibody

    商品详情 参考文献 相关资料
    Name: Anti-ATG4B Antibody
    See all ATG4B primary antibodies
    Description: Rabbit polyclonal antibody to ATG4B
    Specificity: The antibody detects endogenous levels of total ATG4B protein.
    Applications: WB, IHC
    Reactivity: Human, Mouse
    Immunogen: Synthesized peptide derived from internal of human ATG4B.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Concentration: 1.0mg / ml
    Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20?C
    Function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
    Tissue Specificity: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
    Sequence Similarities: Belongs to the peptidase C54 family.
    Cellular locations: Cytoplasm.
    Database Links:
  • Entrez Gene: 23192?Human
  • Entrez Gene: 66615?Mouse
  • Omim: 611338?Human
  • SwissProt: Q9Y4P1?Human
  • SwissProt: Q8BGE6?Mouse
  • Unigene: 283610?Human
  • Unigene: 29087?Mouse
  • Synonyms:
  • APG4 autophagy 4 homolog B Antibody
  • APG4B Antibody
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) Antibody
  • ATG4B Antibody
  • ATG4B_HUMAN Antibody
  • AUT like 1 cysteine endopeptidase Antibody
  • AUT-like 1 cysteine endopeptidase Antibody
  • AUTL1 Antibody
  • Autophagin 1 Antibody
  • Autophagin-1 Antibody
  • Autophagy related 4B cysteine peptidase Antibody
  • Autophagy related cysteine endopeptidase 1 Antibody
  • Autophagy related protein 4 homolog B Antibody
  • Autophagy-related cysteine endopeptidase 1 Antibody
  • Autophagy-related protein 4 homolog B Antibody
  • Cysteine protease ATG4B Antibody
  • hAPG4B Antibody
  • MGC1353 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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