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Anti-PNPLA8 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

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Anti-PNPLA8 Antibody

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Overview

Name:	Anti-PNPLA8 Antibody See all PNPLA8 primary antibodies
Description:	Rabbit polyclonal antibody to PNPLA8
Specificity:	The antibody detects endogenous levels of total PNPLA8 protein.
Applications:	WB
Reactivity:	Human, Mouse
Immunogen:	Synthesized peptide derived from internal of human PNPLA8.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20˚C

Target

Function:	Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.
Tissue Specificity:	Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.
Involvement in Disease:	Mitochondrial myopathy with lactic acidosis: An autosomal recessive disorder characterized by progressive muscle weakness, hypotonia, seizures, poor weight gain, lactic acidosis, and elevated serum pyruvate concentration. Some patients manifest growth failure and moderate neural deafness.
Cellular locations:	Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > Perinuclear region.
Database Links:	Entrez Gene: 50640 Human Entrez Gene: 67452 Mouse Omim: 612123 Human SwissProt: Q9NP80 Human SwissProt: Q8K1N1 Mouse Unigene: 617340 Human Unigene: 732217 Human Unigene: 54126 Mouse
Synonyms:	Calcium-independent phospholipase A2-gamma Antibody Intracellular membrane associated calcium independent phospholipase A2 gamma Antibody Intracellular membrane-associated calcium-independent phospholipase A2 gamma Antibody IPLA2 2 Antibody iPLA2 gamma Antibody IPLA2(GAMMA) Antibody iPLA2-2 Antibody iPLA2-gamma Antibody IPLA22 Antibody IPLA2G Antibody Patatin like phospholipase domain containing protein 8 Antibody Patatin-like phospholipase domain-containing protein 8 Antibody PLPL8_HUMAN Antibody PNPLA-gamma Antibody PNPLA8 Antibody
Information:	Target information shown above is from the UniProt Consortium.